Answer:

$\text{Slope } = \frac{ y_2 - y_1 } { x_2 - x_1 } \\ \frac{-443 - 3}{ 48 - 2} \\ \frac{-446}{ 46} \\ - \frac{223}{23}$

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[SOLVED] What is slope of (2, 3) and (48, -443)?